Since impotence and cardiovascular disorders have similar risk factors, it is essential to realize the cardiovascular effects of erectile dysfunction treatments. In healthy people, phosphodiesterase type 5 inhibitors use triggers insignificant changes in the blood pressure. However, in the vast majority of patients with ED, Tadalafil produced the action similar to placebo. The results of investigations show that Tadalafil should not be combined with nitrates and numerous other medications. Though, generally, the treatment is not associated with any risks for significant cardiovascular change.
The main feature of Tadalafil is its potent action on the muscles and blood circulation. The medication is effective in a great range of patients with impotence, accompanied by diabetes, coronary artery disease, hypertension and vascular disease. Such condition is possible due to the mild and beneficial effect of Tadalafil on the cardiovascular system. Due to the fact the enzyme that is inhibited can be found in muscle cells of systemic veins and arteries all around the body, the agents produce a mild vasodilator effect that influences the cardiovascular system. The process is ultimately precious for patients who are diagnosed with both erectile dysfunction and cardiovascular disorders. Such people have an opportunity to get satisfactory sex and improved cardiovascular disorders.
Tadalafil Effect on Heart Rate and Blood Pressure
Comparing Tadalafil with other erectile dysfunction treatments, it is important to mention its durable effect that lasts over 36 hours. Even though the medication produces a drastic impact on the blood circulation, it does not cause a significant systolic blood pressure drop. The blood pressure change is a bit higher in patients with coronary artery disease, though, generally, Tadalafil is a mild vasodilator that causes a small impact on the arterial pressure. Sure, the change is acceptable for healthy individuals, though it can serve a serious concern for people with hypotension and low blood pressure at baseline. Additionally, it is vital to be aware of Tadalafil interaction with alpha-blockers and nitrates.
Tadalafil Impact on Ischemic Disease and Myocardial Infarction
As a result of multiple tests and trials Tadalafil was approved as a safe and effective ED treatment for patients with coronary artery disease. The medication was given to the people during exercise and none of them experienced ischemia aggravation. An important factor here is that the stress level was similar to the one achieved during sex. Instead, the researches proved Tadalafil to be beneficial on exercise-included ischemia.
As for the risk of myocardial infarction during Tadalafil use, there is a small percent of people with such complication. However, patients are more likely to experience coronary artery disease rather than this condition. Additionally, Tadalafil, as a PDE-5 inhibitor, produces multiple positive therapeutic effects on such cardiovascular disorders as hypertension, cardiovascular disease, congestive heart failure, etc.